review research paper format

Review Paper Format: How To Write A Review Article Fast

This guide aims to demystify the review paper format, presenting practical tips to help you accelerate the writing process. 

From understanding the structure to synthesising literature effectively, we’ll explore how to create a compelling review article swiftly, ensuring your work is both impactful and timely.

Whether you’re a seasoned researcher or a budding scholar, these insights will streamline your writing journey.

Research Paper, Review Paper Format

What is a review paper.

Diving into the realm of scholarly communication, you might have stumbled upon a research review article.

This unique genre serves to synthesise existing data, offering a panoramic view of the current state of knowledge on a particular topic. 

Unlike a standard research article that presents original experiments, a review paper delves into published literature, aiming to: 

• clarify, and
• evaluate previous findings.

Imagine you’re tasked to write a review article. The starting point is often a burning research question. Your mission? To scour various journals, piecing together a well-structured narrative that not only summarises key findings but also identifies gaps in existing literature.

This is where the magic of review writing shines – it’s about creating a roadmap for future research, highlighting areas ripe for exploration.

Review articles come in different flavours, with systematic reviews and meta-analyses being the gold standards. The methodology here is meticulous, with a clear protocol for selecting and evaluating studies.

This rigorous approach ensures that your review is more than just an overview; it’s a critical analysis that adds depth to the understanding of the subject.

Crafting a good review requires mastering the art of citation. Every claim or observation you make needs to be backed by relevant literature. This not only lends credibility to your work but also provides a treasure trove of information for readers eager to delve deeper.

Types Of Review Paper

Not all review articles are created equal. Each type has its methodology, purpose, and format, catering to different research needs and questions.

Systematic Review Paper

First up is the systematic review, the crème de la crème of review types. It’s known for its rigorous methodology, involving a detailed plan for:

• identifying,
• selecting, and
• critically appraising relevant research. 

The aim? To answer a specific research question. Systematic reviews often include meta-analyses, where data from multiple studies are statistically combined to provide more robust conclusions. This review type is a cornerstone in evidence-based fields like healthcare.

Literature Review Paper

Then there’s the literature review, a broader type you might encounter.

Here, the goal is to give an overview of the main points and debates on a topic, without the stringent methodological framework of a systematic review.

Literature reviews are great for getting a grasp of the field and identifying where future research might head. Often reading literature review papers can help you to learn about a topic rather quickly.

Narrative Reviews

Narrative reviews allow for a more flexible approach. Authors of narrative reviews draw on existing literature to provide insights or critique a certain area of research.

This is generally done with a less formal structure than systematic reviews. This type is particularly useful for areas where it’s difficult to quantify findings across studies.

Scoping Reviews

Scoping reviews are gaining traction for their ability to map out the existing literature on a broad topic, identifying:

• key concepts,
• theories, and

Unlike systematic reviews, scoping reviews have a more exploratory approach, which can be particularly useful in emerging fields or for topics that haven’t been comprehensively reviewed before.

Each type of review serves a unique purpose and requires a specific skill set. Whether you’re looking to summarise existing findings, synthesise data for evidence-based practice, or explore new research territories, there’s a review type that fits the bill. 

Knowing how to write, read, and interpret these reviews can significantly enhance your understanding of any research area.

What Are The Parts In A Review Paper

A review paper has a pretty set structure, with minor changes here and there to suit the topic covered. The format not only organises your thoughts but also guides your readers through the complexities of your topic.

Title & Abstract

Starting with the title and abstract, you set the stage. The title should be a concise indicator of the content, making it easier for others to quickly tell what your article content is about.

As for the abstract, it should act as a descriptive summary, offering a snapshot of your review’s scope and findings. 

Introduction

The introduction lays the groundwork, presenting the research question that drives your review. It’s here you:

• justify the importance of your review,
• delineating the current state of knowledge and
• highlighting gaps.

This section aims to articulate the significance of the topic and your objective in exploring it.

Methodology

The methodology section is the backbone of systematic reviews and meta-analyses, detailing the research methods employed to select, assess, and synthesise studies. 

This transparency allows readers to gauge the rigour and reproducibility of your review. It’s a testament to the integrity of your work, showing how you’ve minimised bias.

The heart of your review lies in the body, where you:

• analyse, and
• critique existing literature.

This is where you synthesise evidence, draw connections, and present both sides of any argument. Well-structured paragraphs and clear subheadings guide readers through your analysis, offering insights and fostering a deeper understanding of the subject.

Discussion & Conclusion

The discussion or conclusion section is where you weave together the main points, reflecting on what your findings mean for the field.

It’s about connecting the dots, offering a synthesis of evidence that answers your initial research question. This part often hints at future research directions, suggesting areas that need further exploration due to gaps in existing knowledge.

Lastly, the citation list is your nod to the scholarly community, acknowledging the contributions of others. Each citation is a thread in the larger tapestry of academic discourse, enabling readers to delve deeper into the research that has shaped your review.

Tips To Write An Review Article Fast

Writing a review article quickly without sacrificing quality might seem like a tall order, but with the right approach, it’s entirely achievable. 

Clearly Define Your Research Question

Clearly define your research question. A focused question not only narrows down the scope of your literature search but also keeps your review concise and on track.

By honing in on a specific aspect of a broader topic, you can avoid the common pitfall of becoming overwhelmed by the vast expanse of available literature. This specificity allows you to zero in on the most relevant studies, making your review more impactful.

Efficient Literature Searching

Utilise databases specific to your field and employ advanced search techniques like Boolean operators. This can drastically reduce the time you spend sifting through irrelevant articles.

Additionally, leveraging citation chains—looking at who has cited a pivotal paper in your area and who it cites—can uncover valuable sources you might otherwise miss.

Organise Your Findings Systematically

Developing a robust organisation strategy is key. As you gather sources, categorize them based on themes or methodologies. This not only aids in structuring your review but also in identifying areas where research is lacking or abundant.

Tools like citation management software can be invaluable here, helping you keep track of your sources and their key points. We list out some of the best AI tools for academic research here. 

Build An Outline Before Writing

Don’t underestimate the power of a well-structured outline. A clear blueprint of your article can guide your writing process, ensuring that each section flows logically into the next.

This roadmap not only speeds up the writing process by providing a clear direction but also helps maintain coherence, ensuring your review article delivers a compelling narrative that advances understanding in your field.

Start Writing With The Easiest Sections

When it’s time to write, start with sections you find easiest. This might be the methodology or a particular thematic section where you feel most confident.

Getting words on the page can build momentum, making it easier to tackle more challenging sections later.

Remember, your first draft doesn’t have to be perfect; the goal is to start articulating your synthesis of the literature.

Learn How To Write An Article Review

Mastering the review paper format is a crucial step towards efficient academic writing. By adhering to the structured components outlined, you can streamline the creation of a compelling review article.

Embracing these guidelines not only speeds up the writing process but also enhances the clarity and impact of your work, ensuring your contributions to scholarly discourse are both valuable and timely.

Dr Andrew Stapleton has a Masters and PhD in Chemistry from the UK and Australia. He has many years of research experience and has worked as a Postdoctoral Fellow and Associate at a number of Universities. Although having secured funding for his own research, he left academia to help others with his YouTube channel all about the inner workings of academia and how to make it work for you.

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How to Write a Peer Review

When you write a peer review for a manuscript, what should you include in your comments? What should you leave out? And how should the review be formatted?

This guide provides quick tips for writing and organizing your reviewer report.

Review Outline

Use an outline for your reviewer report so it’s easy for the editors and author to follow. This will also help you keep your comments organized.

Think about structuring your review like an inverted pyramid. Put the most important information at the top, followed by details and examples in the center, and any additional points at the very bottom.

Here’s how your outline might look:

1. Summary of the research and your overall impression

In your own words, summarize what the manuscript claims to report. This shows the editor how you interpreted the manuscript and will highlight any major differences in perspective between you and the other reviewers. Give an overview of the manuscript’s strengths and weaknesses. Think about this as your “take-home” message for the editors. End this section with your recommended course of action.

2. Discussion of specific areas for improvement

It’s helpful to divide this section into two parts: one for major issues and one for minor issues. Within each section, you can talk about the biggest issues first or go systematically figure-by-figure or claim-by-claim. Number each item so that your points are easy to follow (this will also make it easier for the authors to respond to each point). Refer to specific lines, pages, sections, or figure and table numbers so the authors (and editors) know exactly what you’re talking about.

Major vs. minor issues

What’s the difference between a major and minor issue? Major issues should consist of the essential points the authors need to address before the manuscript can proceed. Make sure you focus on what is  fundamental for the current study . In other words, it’s not helpful to recommend additional work that would be considered the “next step” in the study. Minor issues are still important but typically will not affect the overall conclusions of the manuscript. Here are some examples of what would might go in the “minor” category:

• Missing references (but depending on what is missing, this could also be a major issue)
• Technical clarifications (e.g., the authors should clarify how a reagent works)
• Data presentation (e.g., the authors should present p-values differently)
• Typos, spelling, grammar, and phrasing issues

3. Any other points

Confidential comments for the editors.

Some journals have a space for reviewers to enter confidential comments about the manuscript. Use this space to mention concerns about the submission that you’d want the editors to consider before sharing your feedback with the authors, such as concerns about ethical guidelines or language quality. Any serious issues should be raised directly and immediately with the journal as well.

This section is also where you will disclose any potentially competing interests, and mention whether you’re willing to look at a revised version of the manuscript.

Do not use this space to critique the manuscript, since comments entered here will not be passed along to the authors.  If you’re not sure what should go in the confidential comments, read the reviewer instructions or check with the journal first before submitting your review. If you are reviewing for a journal that does not offer a space for confidential comments, consider writing to the editorial office directly with your concerns.

Get this outline in a template

Giving Feedback

Giving feedback is hard. Giving effective feedback can be even more challenging. Remember that your ultimate goal is to discuss what the authors would need to do in order to qualify for publication. The point is not to nitpick every piece of the manuscript. Your focus should be on providing constructive and critical feedback that the authors can use to improve their study.

If you’ve ever had your own work reviewed, you already know that it’s not always easy to receive feedback. Follow the golden rule: Write the type of review you’d want to receive if you were the author. Even if you decide not to identify yourself in the review, you should write comments that you would be comfortable signing your name to.

In your comments, use phrases like “ the authors’ discussion of X” instead of “ your discussion of X .” This will depersonalize the feedback and keep the focus on the manuscript instead of the authors.

General guidelines for effective feedback

• Justify your recommendation with concrete evidence and specific examples.
• Be specific so the authors know what they need to do to improve.
• Be thorough. This might be the only time you read the manuscript.
• Be professional and respectful. The authors will be reading these comments too.
• Remember to say what you liked about the manuscript!

Don’t

• Recommend additional experiments or  unnecessary elements that are out of scope for the study or for the journal criteria.
• Tell the authors exactly how to revise their manuscript—you don’t need to do their work for them.
• Use the review to promote your own research or hypotheses.
• Focus on typos and grammar. If the manuscript needs significant editing for language and writing quality, just mention this in your comments.
• Submit your review without proofreading it and checking everything one more time.

Before and After: Sample Reviewer Comments

Keeping in mind the guidelines above, how do you put your thoughts into words? Here are some sample “before” and “after” reviewer comments

✗ Before

“The authors appear to have no idea what they are talking about. I don’t think they have read any of the literature on this topic.”

✓ After

“The study fails to address how the findings relate to previous research in this area. The authors should rewrite their Introduction and Discussion to reference the related literature, especially recently published work such as Darwin et al.”

“The writing is so bad, it is practically unreadable. I could barely bring myself to finish it.”

“While the study appears to be sound, the language is unclear, making it difficult to follow. I advise the authors work with a writing coach or copyeditor to improve the flow and readability of the text.”

“It’s obvious that this type of experiment should have been included. I have no idea why the authors didn’t use it. This is a big mistake.”

“The authors are off to a good start, however, this study requires additional experiments, particularly [type of experiment]. Alternatively, the authors should include more information that clarifies and justifies their choice of methods.”

Suggested Language for Tricky Situations

You might find yourself in a situation where you’re not sure how to explain the problem or provide feedback in a constructive and respectful way. Here is some suggested language for common issues you might experience.

What you think : The manuscript is fatally flawed. What you could say: “The study does not appear to be sound” or “the authors have missed something crucial”.

What you think : You don’t completely understand the manuscript. What you could say : “The authors should clarify the following sections to avoid confusion…”

What you think : The technical details don’t make sense. What you could say : “The technical details should be expanded and clarified to ensure that readers understand exactly what the researchers studied.”

What you think: The writing is terrible. What you could say : “The authors should revise the language to improve readability.”

What you think : The authors have over-interpreted the findings. What you could say : “The authors aim to demonstrate [XYZ], however, the data does not fully support this conclusion. Specifically…”

What does a good review look like?

Check out the peer review examples at F1000 Research to see how other reviewers write up their reports and give constructive feedback to authors.

Time to Submit the Review!

Be sure you turn in your report on time. Need an extension? Tell the journal so that they know what to expect. If you need a lot of extra time, the journal might need to contact other reviewers or notify the author about the delay.

Tip: Building a relationship with an editor

You’ll be more likely to be asked to review again if you provide high-quality feedback and if you turn in the review on time. Especially if it’s your first review for a journal, it’s important to show that you are reliable. Prove yourself once and you’ll get asked to review again!

• Getting started as a reviewer
• Responding to an invitation
• Reading a manuscript
• Writing a peer review

The contents of the Peer Review Center are also available as a live, interactive training session, complete with slides, talking points, and activities. …

The contents of the Writing Center are also available as a live, interactive training session, complete with slides, talking points, and activities. …

There’s a lot to consider when deciding where to submit your work. Learn how to choose a journal that will help your study reach its audience, while reflecting your values as a researcher…

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• CAREER FEATURE
• 04 December 2020
• Correction 09 December 2020

How to write a superb literature review

Andy Tay is a freelance writer based in Singapore.

You can also search for this author in PubMed   Google Scholar

Literature reviews are important resources for scientists. They provide historical context for a field while offering opinions on its future trajectory. Creating them can provide inspiration for one’s own research, as well as some practice in writing. But few scientists are trained in how to write a review — or in what constitutes an excellent one. Even picking the appropriate software to use can be an involved decision (see ‘Tools and techniques’). So Nature asked editors and working scientists with well-cited reviews for their tips.

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doi: https://doi.org/10.1038/d41586-020-03422-x

Interviews have been edited for length and clarity.

Updates & Corrections

Correction 09 December 2020 : An earlier version of the tables in this article included some incorrect details about the programs Zotero, Endnote and Manubot. These have now been corrected.

Hsing, I.-M., Xu, Y. & Zhao, W. Electroanalysis 19 , 755–768 (2007).

Article   Google Scholar  

Ledesma, H. A. et al. Nature Nanotechnol. 14 , 645–657 (2019).

Article   PubMed   Google Scholar  

Brahlek, M., Koirala, N., Bansal, N. & Oh, S. Solid State Commun. 215–216 , 54–62 (2015).

Choi, Y. & Lee, S. Y. Nature Rev. Chem . https://doi.org/10.1038/s41570-020-00221-w (2020).

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How to Write a Best Review Paper to Get More Citation

Review Paper Writing Guide

Are you new to academia? Do you want to learn how to write a good review paper to get in-depth knowledge about your domain? you are at the right place. In this article, you will learn how to write the best review paper in a step-by-step systematic procedure with a sample review article format to get more Citation.

What is a Review Paper?

A review paper, or a literature review , is a thorough, analytical examination of previously published literature. It also provides an overview of current research works on a particular topic in chronological order.

• The main objective of writing a review paper is to evaluate the existing data or results, which can be done through analysis, modeling, classification, comparison, and summary.  
• Review papers can help to identify the research gaps, to explore potential areas in a particular field.
• It helps to come out with new conclusions from already published works.
• Any scholar or researcher or scientist who wants to carry out research on a specific theme, first read the review articles relevant to that research area to understand the research gap for arriving at the problem statement.
• Writing a review article provides clarity, novelty, and contribution to the area of research and it demands a great level of in-depth understanding of the subject and a well-structured arrangement of discussions and arguments.
• Some journals publish only review papers, and they do not accept research articles. It is important to check the journal submission guidelines.

Difference Between a Review Paper and a Research Paper

The difference between a review paper and a research paper is presented below.

6 T ypes of Review Papers

The review papers are classified in to six main categories based on the theme and it is presented in the figure below.

Purpose of Review Paper

The purpose of a review paper is to assess a particular research question, theoretical or practical approach which provides readers with in-depth knowledge and state-of-the-art understanding of the research area.

The purpose of the review paper can vary based on their specific type and research needs.

• Provide a unified, collective overview of the current state of knowledge on a specific research topic and provide an inclusive foundation on a research theme.
• Identify ambiguity, and contradictions in existing results or data.
• Highlight the existing methodological approaches, research techniques, and unique perceptions.
• Develop theoretical outlines to resolve and work on published research.
• Discuss research gaps and future perspectives.

Criteria for Good Review Paper

A good review paper needs to achieve three important criteria. ( Palmatier et al 2017 ).

• First, the area of research should be suitable for writing a review paper so that the author finds sufficient published literature.
• The review paper should be written with suitable literature, detailed discussion, sufficient data/results to support the interpretation, and persuasive language style.
• A completed review paper should provide substantial new innovative ideas to the readers based on the comparison of published works.

Review papers are widely read by many researchers and it helps to get more citations for author. So, it is important to learn how to write a review paper and find a journal to publish .

Step-by-Step Systematic Procedure to Write a Review Paper

Time needed:  20 days and 7 hours

The systematic procedural steps to write the best review paper are as follows:

Select a suitable area in your research field formulate clear objectives, and prepare the specific research hypotheses that are to be explored.

Designing your research work is an important step for any researcher. Based on the objectives, develop a clear methodology or protocol to review a review paper.

Thorough analysis and understanding of different published works help the author to identify suitable and relevant data/results that will be used to write the paper.

The degree of analysis to evaluate the collected data varies by extensive review. The examination of trends, patterns, ideas, comparisons, and relationships in the study provides deeper knowledge on that area of research .

Interpretation of results is very important for a good review paper. The author should present the discussion systematically without any ambiguity. The results can be presented in descriptive form, tables, and figures. The new insights should have an in-depth discussion of the topic in line with fundamentals. Finally, the author is expected to present the limitations of the existing study with future perspectives.

Sample Review Article Format

Title, abstract, keywords.

Write an effective and suitable title, abstract, and keywords relevant to your review paper. This will maximize the visibility of your paper online for the readers to find your work. Your title and abstract should be clear, concise, appropriate, and informative.

Introduction

Present a detailed introduction to your research which is published in chronological order in your own words. Don’t summarize the published literature. The introduction should encourage the readers to read your paper.

Various topics to discuss the critical issues

Make sure you present a critical discussion, not a descriptive summary of the topic. If there is contradictory research in your area of research, verify to include an element of debate and present both sides of the argument. A good review paper can resolve the conflict between contradictory works.

Conclusion and Future Perspectives

The written review paper should achieve your objectives. Hence, the review paper should leave the reader with a clear understanding of the following questions:

What they can understand from the review paper?

What still remains a requirement of further investigation in the research area?

This can include making suggestions for future scope on the theme as part of your conclusion.

Acknowledgment       

The authors can submit a brief acknowledgment of any financial, instrumentation, and academic support received about research work.

Citing references at appropriate places in the article is necessary and important to avoid plagiarism. Each journal has its referencing style. Therefore, the references need to be listed at the end of the manuscript. The number of references in the review paper is usually higher than in a research paper .

I hope this article will give you a clear idea of how to write a review paper. Please give your valuable comments.

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Nice thank you for your clarification

How to write a review paper on the relevant of science to education

This blog is very informative. Is it true that an increase in the number of citations improves the quality and impact of a review paper?

Thanks for your ideas. Really helpful

it was very well information

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How to write a good scientific review article

Affiliation.

• 1 The FEBS Journal Editorial Office, Cambridge, UK.
• PMID: 35792782
• DOI: 10.1111/febs.16565

Literature reviews are valuable resources for the scientific community. With research accelerating at an unprecedented speed in recent years and more and more original papers being published, review articles have become increasingly important as a means to keep up to date with developments in a particular area of research. A good review article provides readers with an in-depth understanding of a field and highlights key gaps and challenges to address with future research. Writing a review article also helps to expand the writer's knowledge of their specialist area and to develop their analytical and communication skills, amongst other benefits. Thus, the importance of building review-writing into a scientific career cannot be overstated. In this instalment of The FEBS Journal's Words of Advice series, I provide detailed guidance on planning and writing an informative and engaging literature review.

© 2022 Federation of European Biochemical Societies.

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How to write a review article?

In the medical sciences, the importance of review articles is rising. When clinicians want to update their knowledge and generate guidelines about a topic, they frequently use reviews as a starting point. The value of a review is associated with what has been done, what has been found and how these findings are presented. Before asking ‘how,’ the question of ‘why’ is more important when starting to write a review. The main and fundamental purpose of writing a review is to create a readable synthesis of the best resources available in the literature for an important research question or a current area of research. Although the idea of writing a review is attractive, it is important to spend time identifying the important questions. Good review methods are critical because they provide an unbiased point of view for the reader regarding the current literature. There is a consensus that a review should be written in a systematic fashion, a notion that is usually followed. In a systematic review with a focused question, the research methods must be clearly described. A ‘methodological filter’ is the best method for identifying the best working style for a research question, and this method reduces the workload when surveying the literature. An essential part of the review process is differentiating good research from bad and leaning on the results of the better studies. The ideal way to synthesize studies is to perform a meta-analysis. In conclusion, when writing a review, it is best to clearly focus on fixed ideas, to use a procedural and critical approach to the literature and to express your findings in an attractive way.

The importance of review articles in health sciences is increasing day by day. Clinicians frequently benefit from review articles to update their knowledge in their field of specialization, and use these articles as a starting point for formulating guidelines. [ 1 , 2 ] The institutions which provide financial support for further investigations resort to these reviews to reveal the need for these researches. [ 3 ] As is the case with all other researches, the value of a review article is related to what is achieved, what is found, and the way of communicating this information. A few studies have evaluated the quality of review articles. Murlow evaluated 50 review articles published in 1985, and 1986, and revealed that none of them had complied with clear-cut scientific criteria. [ 4 ] In 1996 an international group that analyzed articles, demonstrated the aspects of review articles, and meta-analyses that had not complied with scientific criteria, and elaborated QUOROM (QUality Of Reporting Of Meta-analyses) statement which focused on meta-analyses of randomized controlled studies. [ 5 ] Later on this guideline was updated, and named as PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses). [ 6 ]

Review articles are divided into 2 categories as narrative, and systematic reviews. Narrative reviews are written in an easily readable format, and allow consideration of the subject matter within a large spectrum. However in a systematic review, a very detailed, and comprehensive literature surveying is performed on the selected topic. [ 7 , 8 ] Since it is a result of a more detailed literature surveying with relatively lesser involvement of author’s bias, systematic reviews are considered as gold standard articles. Systematic reviews can be diivded into qualitative, and quantitative reviews. In both of them detailed literature surveying is performed. However in quantitative reviews, study data are collected, and statistically evaluated (ie. meta-analysis). [ 8 ]

Before inquring for the method of preparation of a review article, it is more logical to investigate the motivation behind writing the review article in question. The fundamental rationale of writing a review article is to make a readable synthesis of the best literature sources on an important research inquiry or a topic. This simple definition of a review article contains the following key elements:

• The question(s) to be dealt with
• Methods used to find out, and select the best quality researches so as to respond to these questions.
• To synthetize available, but quite different researches

For the specification of important questions to be answered, number of literature references to be consulted should be more or less determined. Discussions should be conducted with colleagues in the same area of interest, and time should be reserved for the solution of the problem(s). Though starting to write the review article promptly seems to be very alluring, the time you spend for the determination of important issues won’t be a waste of time. [ 9 ]

The PRISMA statement [ 6 ] elaborated to write a well-designed review articles contains a 27-item checklist ( Table 1 ). It will be reasonable to fulfill the requirements of these items during preparation of a review article or a meta-analysis. Thus preparation of a comprehensible article with a high-quality scientific content can be feasible.

PRISMA statement: A 27-item checklist

Contents and format

Important differences exist between systematic, and non-systematic reviews which especially arise from methodologies used in the description of the literature sources. A non-systematic review means use of articles collected for years with the recommendations of your colleagues, while systematic review is based on struggles to search for, and find the best possible researches which will respond to the questions predetermined at the start of the review.

Though a consensus has been reached about the systematic design of the review articles, studies revealed that most of them had not been written in a systematic format. McAlister et al. analyzed review articles in 6 medical journals, and disclosed that in less than one fourth of the review articles, methods of description, evaluation or synthesis of evidence had been provided, one third of them had focused on a clinical topic, and only half of them had provided quantitative data about the extend of the potential benefits. [ 10 ]

Use of proper methodologies in review articles is important in that readers assume an objective attitude towards updated information. We can confront two problems while we are using data from researches in order to answer certain questions. Firstly, we can be prejudiced during selection of research articles or these articles might be biased. To minimize this risk, methodologies used in our reviews should allow us to define, and use researches with minimal degree of bias. The second problem is that, most of the researches have been performed with small sample sizes. In statistical methods in meta-analyses, available researches are combined to increase the statistical power of the study. The problematic aspect of a non-systematic review is that our tendency to give biased responses to the questions, in other words we apt to select the studies with known or favourite results, rather than the best quality investigations among them.

As is the case with many research articles, general format of a systematic review on a single subject includes sections of Introduction, Methods, Results, and Discussion ( Table 2 ).

Structure of a systematic review

Preparation of the review article

Steps, and targets of constructing a good review article are listed in Table 3 . To write a good review article the items in Table 3 should be implemented step by step. [ 11 – 13 ]

Steps of a systematic review

The research question

It might be helpful to divide the research question into components. The most prevalently used format for questions related to the treatment is PICO (P - Patient, Problem or Population; I-Intervention; C-appropriate Comparisons, and O-Outcome measures) procedure. For example In female patients (P) with stress urinary incontinence, comparisons (C) between transobturator, and retropubic midurethral tension-free band surgery (I) as for patients’ satisfaction (O).

Finding Studies

In a systematic review on a focused question, methods of investigation used should be clearly specified.

Ideally, research methods, investigated databases, and key words should be described in the final report. Different databases are used dependent on the topic analyzed. In most of the clinical topics, Medline should be surveyed. However searching through Embase and CINAHL can be also appropriate.

While determining appropriate terms for surveying, PICO elements of the issue to be sought may guide the process. Since in general we are interested in more than one outcome, P, and I can be key elements. In this case we should think about synonyms of P, and I elements, and combine them with a conjunction AND.

One method which might alleviate the workload of surveying process is “methodological filter” which aims to find the best investigation method for each research question. A good example of this method can be found in PubMed interface of Medline. The Clinical Queries tool offers empirically developed filters for five different inquiries as guidelines for etiology, diagnosis, treatment, prognosis or clinical prediction.

Evaluation of the Quality of the Study

As an indispensable component of the review process is to discriminate good, and bad quality researches from each other, and the outcomes should be based on better qualified researches, as far as possible. To achieve this goal you should know the best possible evidence for each type of question The first component of the quality is its general planning/design of the study. General planning/design of a cohort study, a case series or normal study demonstrates variations.

A hierarchy of evidence for different research questions is presented in Table 4 . However this hierarchy is only a first step. After you find good quality research articles, you won’t need to read all the rest of other articles which saves you tons of time. [ 14 ]

Determination of levels of evidence based on the type of the research question

Formulating a Synthesis

Rarely all researches arrive at the same conclusion. In this case a solution should be found. However it is risky to make a decision based on the votes of absolute majority. Indeed, a well-performed large scale study, and a weakly designed one are weighed on the same scale. Therefore, ideally a meta-analysis should be performed to solve apparent differences. Ideally, first of all, one should be focused on the largest, and higher quality study, then other studies should be compared with this basic study.

Conclusions

In conclusion, during writing process of a review article, the procedures to be achieved can be indicated as follows: 1) Get rid of fixed ideas, and obsessions from your head, and view the subject from a large perspective. 2) Research articles in the literature should be approached with a methodological, and critical attitude and 3) finally data should be explained in an attractive way.

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Writing a Literature Review

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A literature review is a document or section of a document that collects key sources on a topic and discusses those sources in conversation with each other (also called synthesis ). The lit review is an important genre in many disciplines, not just literature (i.e., the study of works of literature such as novels and plays). When we say “literature review” or refer to “the literature,” we are talking about the research ( scholarship ) in a given field. You will often see the terms “the research,” “the scholarship,” and “the literature” used mostly interchangeably.

Where, when, and why would I write a lit review?

There are a number of different situations where you might write a literature review, each with slightly different expectations; different disciplines, too, have field-specific expectations for what a literature review is and does. For instance, in the humanities, authors might include more overt argumentation and interpretation of source material in their literature reviews, whereas in the sciences, authors are more likely to report study designs and results in their literature reviews; these differences reflect these disciplines’ purposes and conventions in scholarship. You should always look at examples from your own discipline and talk to professors or mentors in your field to be sure you understand your discipline’s conventions, for literature reviews as well as for any other genre.

A literature review can be a part of a research paper or scholarly article, usually falling after the introduction and before the research methods sections. In these cases, the lit review just needs to cover scholarship that is important to the issue you are writing about; sometimes it will also cover key sources that informed your research methodology.

Lit reviews can also be standalone pieces, either as assignments in a class or as publications. In a class, a lit review may be assigned to help students familiarize themselves with a topic and with scholarship in their field, get an idea of the other researchers working on the topic they’re interested in, find gaps in existing research in order to propose new projects, and/or develop a theoretical framework and methodology for later research. As a publication, a lit review usually is meant to help make other scholars’ lives easier by collecting and summarizing, synthesizing, and analyzing existing research on a topic. This can be especially helpful for students or scholars getting into a new research area, or for directing an entire community of scholars toward questions that have not yet been answered.

What are the parts of a lit review?

Most lit reviews use a basic introduction-body-conclusion structure; if your lit review is part of a larger paper, the introduction and conclusion pieces may be just a few sentences while you focus most of your attention on the body. If your lit review is a standalone piece, the introduction and conclusion take up more space and give you a place to discuss your goals, research methods, and conclusions separately from where you discuss the literature itself.

Introduction:

• An introductory paragraph that explains what your working topic and thesis is
• A forecast of key topics or texts that will appear in the review
• Potentially, a description of how you found sources and how you analyzed them for inclusion and discussion in the review (more often found in published, standalone literature reviews than in lit review sections in an article or research paper)
• Summarize and synthesize: Give an overview of the main points of each source and combine them into a coherent whole
• Analyze and interpret: Don’t just paraphrase other researchers – add your own interpretations where possible, discussing the significance of findings in relation to the literature as a whole
• Critically Evaluate: Mention the strengths and weaknesses of your sources
• Write in well-structured paragraphs: Use transition words and topic sentence to draw connections, comparisons, and contrasts.

Conclusion:

• Summarize the key findings you have taken from the literature and emphasize their significance
• Connect it back to your primary research question

How should I organize my lit review?

Lit reviews can take many different organizational patterns depending on what you are trying to accomplish with the review. Here are some examples:

• Chronological : The simplest approach is to trace the development of the topic over time, which helps familiarize the audience with the topic (for instance if you are introducing something that is not commonly known in your field). If you choose this strategy, be careful to avoid simply listing and summarizing sources in order. Try to analyze the patterns, turning points, and key debates that have shaped the direction of the field. Give your interpretation of how and why certain developments occurred (as mentioned previously, this may not be appropriate in your discipline — check with a teacher or mentor if you’re unsure).
• Thematic : If you have found some recurring central themes that you will continue working with throughout your piece, you can organize your literature review into subsections that address different aspects of the topic. For example, if you are reviewing literature about women and religion, key themes can include the role of women in churches and the religious attitude towards women.
• Qualitative versus quantitative research
• Empirical versus theoretical scholarship
• Divide the research by sociological, historical, or cultural sources
• Theoretical : In many humanities articles, the literature review is the foundation for the theoretical framework. You can use it to discuss various theories, models, and definitions of key concepts. You can argue for the relevance of a specific theoretical approach or combine various theorical concepts to create a framework for your research.

What are some strategies or tips I can use while writing my lit review?

Any lit review is only as good as the research it discusses; make sure your sources are well-chosen and your research is thorough. Don’t be afraid to do more research if you discover a new thread as you’re writing. More info on the research process is available in our "Conducting Research" resources .

As you’re doing your research, create an annotated bibliography ( see our page on the this type of document ). Much of the information used in an annotated bibliography can be used also in a literature review, so you’ll be not only partially drafting your lit review as you research, but also developing your sense of the larger conversation going on among scholars, professionals, and any other stakeholders in your topic.

Usually you will need to synthesize research rather than just summarizing it. This means drawing connections between sources to create a picture of the scholarly conversation on a topic over time. Many student writers struggle to synthesize because they feel they don’t have anything to add to the scholars they are citing; here are some strategies to help you:

• It often helps to remember that the point of these kinds of syntheses is to show your readers how you understand your research, to help them read the rest of your paper.
• Writing teachers often say synthesis is like hosting a dinner party: imagine all your sources are together in a room, discussing your topic. What are they saying to each other?
• Look at the in-text citations in each paragraph. Are you citing just one source for each paragraph? This usually indicates summary only. When you have multiple sources cited in a paragraph, you are more likely to be synthesizing them (not always, but often
• Read more about synthesis here.

The most interesting literature reviews are often written as arguments (again, as mentioned at the beginning of the page, this is discipline-specific and doesn’t work for all situations). Often, the literature review is where you can establish your research as filling a particular gap or as relevant in a particular way. You have some chance to do this in your introduction in an article, but the literature review section gives a more extended opportunity to establish the conversation in the way you would like your readers to see it. You can choose the intellectual lineage you would like to be part of and whose definitions matter most to your thinking (mostly humanities-specific, but this goes for sciences as well). In addressing these points, you argue for your place in the conversation, which tends to make the lit review more compelling than a simple reporting of other sources.

Page Content

Overview of the review report format, the first read-through, first read considerations, spotting potential major flaws, concluding the first reading, rejection after the first reading, before starting the second read-through, doing the second read-through, the second read-through: section by section guidance, how to structure your report, on presentation and style, criticisms & confidential comments to editors, the recommendation, when recommending rejection, additional resources, step by step guide to reviewing a manuscript.

When you receive an invitation to peer review, you should be sent a copy of the paper's abstract to help you decide whether you wish to do the review. Try to respond to invitations promptly - it will prevent delays. It is also important at this stage to declare any potential Conflict of Interest.

The structure of the review report varies between journals. Some follow an informal structure, while others have a more formal approach.

" Number your comments!!! " (Jonathon Halbesleben, former Editor of Journal of Occupational and Organizational Psychology)

Informal Structure

Many journals don't provide criteria for reviews beyond asking for your 'analysis of merits'. In this case, you may wish to familiarize yourself with examples of other reviews done for the journal, which the editor should be able to provide or, as you gain experience, rely on your own evolving style.

Formal Structure

Other journals require a more formal approach. Sometimes they will ask you to address specific questions in your review via a questionnaire. Or they might want you to rate the manuscript on various attributes using a scorecard. Often you can't see these until you log in to submit your review. So when you agree to the work, it's worth checking for any journal-specific guidelines and requirements. If there are formal guidelines, let them direct the structure of your review.

In Both Cases

Whether specifically required by the reporting format or not, you should expect to compile comments to authors and possibly confidential ones to editors only.

Following the invitation to review, when you'll have received the article abstract, you should already understand the aims, key data and conclusions of the manuscript. If you don't, make a note now that you need to feedback on how to improve those sections.

The first read-through is a skim-read. It will help you form an initial impression of the paper and get a sense of whether your eventual recommendation will be to accept or reject the paper.

Keep a pen and paper handy when skim-reading.

Try to bear in mind the following questions - they'll help you form your overall impression:

• What is the main question addressed by the research? Is it relevant and interesting?
• How original is the topic? What does it add to the subject area compared with other published material?
• Is the paper well written? Is the text clear and easy to read?
• Are the conclusions consistent with the evidence and arguments presented? Do they address the main question posed?
• If the author is disagreeing significantly with the current academic consensus, do they have a substantial case? If not, what would be required to make their case credible?
• If the paper includes tables or figures, what do they add to the paper? Do they aid understanding or are they superfluous?

While you should read the whole paper, making the right choice of what to read first can save time by flagging major problems early on.

Editors say, " Specific recommendations for remedying flaws are VERY welcome ."

Examples of possibly major flaws include:

• Drawing a conclusion that is contradicted by the author's own statistical or qualitative evidence
• The use of a discredited method
• Ignoring a process that is known to have a strong influence on the area under study

If experimental design features prominently in the paper, first check that the methodology is sound - if not, this is likely to be a major flaw.

You might examine:

• The sampling in analytical papers
• The sufficient use of control experiments
• The precision of process data
• The regularity of sampling in time-dependent studies
• The validity of questions, the use of a detailed methodology and the data analysis being done systematically (in qualitative research)
• That qualitative research extends beyond the author's opinions, with sufficient descriptive elements and appropriate quotes from interviews or focus groups

Major Flaws in Information

If methodology is less of an issue, it's often a good idea to look at the data tables, figures or images first. Especially in science research, it's all about the information gathered. If there are critical flaws in this, it's very likely the manuscript will need to be rejected. Such issues include:

• Insufficient data
• Unclear data tables
• Contradictory data that either are not self-consistent or disagree with the conclusions
• Confirmatory data that adds little, if anything, to current understanding - unless strong arguments for such repetition are made

If you find a major problem, note your reasoning and clear supporting evidence (including citations).

After the initial read and using your notes, including those of any major flaws you found, draft the first two paragraphs of your review - the first summarizing the research question addressed and the second the contribution of the work. If the journal has a prescribed reporting format, this draft will still help you compose your thoughts.

The First Paragraph

This should state the main question addressed by the research and summarize the goals, approaches, and conclusions of the paper. It should:

• Help the editor properly contextualize the research and add weight to your judgement
• Show the author what key messages are conveyed to the reader, so they can be sure they are achieving what they set out to do
• Focus on successful aspects of the paper so the author gets a sense of what they've done well

The Second Paragraph

This should provide a conceptual overview of the contribution of the research. So consider:

• Is the paper's premise interesting and important?
• Are the methods used appropriate?
• Do the data support the conclusions?

After drafting these two paragraphs, you should be in a position to decide whether this manuscript is seriously flawed and should be rejected (see the next section). Or whether it is publishable in principle and merits a detailed, careful read through.

Even if you are coming to the opinion that an article has serious flaws, make sure you read the whole paper. This is very important because you may find some really positive aspects that can be communicated to the author. This could help them with future submissions.

A full read-through will also make sure that any initial concerns are indeed correct and fair. After all, you need the context of the whole paper before deciding to reject. If you still intend to recommend rejection, see the section "When recommending rejection."

Once the paper has passed your first read and you've decided the article is publishable in principle, one purpose of the second, detailed read-through is to help prepare the manuscript for publication. You may still decide to recommend rejection following a second reading.

" Offer clear suggestions for how the authors can address the concerns raised. In other words, if you're going to raise a problem, provide a solution ." (Jonathon Halbesleben, Editor of Journal of Occupational and Organizational Psychology)

Preparation

To save time and simplify the review:

• Don't rely solely upon inserting comments on the manuscript document - make separate notes
• Try to group similar concerns or praise together
• If using a review program to note directly onto the manuscript, still try grouping the concerns and praise in separate notes - it helps later
• Note line numbers of text upon which your notes are based - this helps you find items again and also aids those reading your review

Now that you have completed your preparations, you're ready to spend an hour or so reading carefully through the manuscript.

As you're reading through the manuscript for a second time, you'll need to keep in mind the argument's construction, the clarity of the language and content.

With regard to the argument’s construction, you should identify:

• Any places where the meaning is unclear or ambiguous
• Any factual errors
• Any invalid arguments

You may also wish to consider:

• Does the title properly reflect the subject of the paper?
• Does the abstract provide an accessible summary of the paper?
• Do the keywords accurately reflect the content?
• Is the paper an appropriate length?
• Are the key messages short, accurate and clear?

Not every submission is well written. Part of your role is to make sure that the text’s meaning is clear.

Editors say, " If a manuscript has many English language and editing issues, please do not try and fix it. If it is too bad, note that in your review and it should be up to the authors to have the manuscript edited ."

If the article is difficult to understand, you should have rejected it already. However, if the language is poor but you understand the core message, see if you can suggest improvements to fix the problem:

• Are there certain aspects that could be communicated better, such as parts of the discussion?
• Should the authors consider resubmitting to the same journal after language improvements?
• Would you consider looking at the paper again once these issues are dealt with?

On Grammar and Punctuation

Your primary role is judging the research content. Don't spend time polishing grammar or spelling. Editors will make sure that the text is at a high standard before publication. However, if you spot grammatical errors that affect clarity of meaning, then it's important to highlight these. Expect to suggest such amendments - it's rare for a manuscript to pass review with no corrections.

A 2010 study of nursing journals found that 79% of recommendations by reviewers were influenced by grammar and writing style (Shattel, et al., 2010).

1. The Introduction

A well-written introduction:

• Sets out the argument
• Summarizes recent research related to the topic
• Highlights gaps in current understanding or conflicts in current knowledge
• Establishes the originality of the research aims by demonstrating the need for investigations in the topic area
• Gives a clear idea of the target readership, why the research was carried out and the novelty and topicality of the manuscript

Originality and Topicality

Originality and topicality can only be established in the light of recent authoritative research. For example, it's impossible to argue that there is a conflict in current understanding by referencing articles that are 10 years old.

Authors may make the case that a topic hasn't been investigated in several years and that new research is required. This point is only valid if researchers can point to recent developments in data gathering techniques or to research in indirectly related fields that suggest the topic needs revisiting. Clearly, authors can only do this by referencing recent literature. Obviously, where older research is seminal or where aspects of the methodology rely upon it, then it is perfectly appropriate for authors to cite some older papers.

Editors say, "Is the report providing new information; is it novel or just confirmatory of well-known outcomes ?"

It's common for the introduction to end by stating the research aims. By this point you should already have a good impression of them - if the explicit aims come as a surprise, then the introduction needs improvement.

2. Materials and Methods

Academic research should be replicable, repeatable and robust - and follow best practice.

Replicable Research

This makes sufficient use of:

• Control experiments
• Repeated analyses
• Repeated experiments

These are used to make sure observed trends are not due to chance and that the same experiment could be repeated by other researchers - and result in the same outcome. Statistical analyses will not be sound if methods are not replicable. Where research is not replicable, the paper should be recommended for rejection.

Repeatable Methods

These give enough detail so that other researchers are able to carry out the same research. For example, equipment used or sampling methods should all be described in detail so that others could follow the same steps. Where methods are not detailed enough, it's usual to ask for the methods section to be revised.

Robust Research

This has enough data points to make sure the data are reliable. If there are insufficient data, it might be appropriate to recommend revision. You should also consider whether there is any in-built bias not nullified by the control experiments.

Best Practice

During these checks you should keep in mind best practice:

• Standard guidelines were followed (e.g. the CONSORT Statement for reporting randomized trials)
• The health and safety of all participants in the study was not compromised
• Ethical standards were maintained

If the research fails to reach relevant best practice standards, it's usual to recommend rejection. What's more, you don't then need to read any further.

3. Results and Discussion

This section should tell a coherent story - What happened? What was discovered or confirmed?

Certain patterns of good reporting need to be followed by the author:

• They should start by describing in simple terms what the data show
• They should make reference to statistical analyses, such as significance or goodness of fit
• Once described, they should evaluate the trends observed and explain the significance of the results to wider understanding. This can only be done by referencing published research
• The outcome should be a critical analysis of the data collected

Discussion should always, at some point, gather all the information together into a single whole. Authors should describe and discuss the overall story formed. If there are gaps or inconsistencies in the story, they should address these and suggest ways future research might confirm the findings or take the research forward.

4. Conclusions

This section is usually no more than a few paragraphs and may be presented as part of the results and discussion, or in a separate section. The conclusions should reflect upon the aims - whether they were achieved or not - and, just like the aims, should not be surprising. If the conclusions are not evidence-based, it's appropriate to ask for them to be re-written.

5. Information Gathered: Images, Graphs and Data Tables

If you find yourself looking at a piece of information from which you cannot discern a story, then you should ask for improvements in presentation. This could be an issue with titles, labels, statistical notation or image quality.

Where information is clear, you should check that:

• The results seem plausible, in case there is an error in data gathering
• The trends you can see support the paper's discussion and conclusions
• There are sufficient data. For example, in studies carried out over time are there sufficient data points to support the trends described by the author?

You should also check whether images have been edited or manipulated to emphasize the story they tell. This may be appropriate but only if authors report on how the image has been edited (e.g. by highlighting certain parts of an image). Where you feel that an image has been edited or manipulated without explanation, you should highlight this in a confidential comment to the editor in your report.

6. List of References

You will need to check referencing for accuracy, adequacy and balance.

Where a cited article is central to the author's argument, you should check the accuracy and format of the reference - and bear in mind different subject areas may use citations differently. Otherwise, it's the editor’s role to exhaustively check the reference section for accuracy and format.

You should consider if the referencing is adequate:

• Are important parts of the argument poorly supported?
• Are there published studies that show similar or dissimilar trends that should be discussed?
• If a manuscript only uses half the citations typical in its field, this may be an indicator that referencing should be improved - but don't be guided solely by quantity
• References should be relevant, recent and readily retrievable

Check for a well-balanced list of references that is:

• Helpful to the reader
• Fair to competing authors
• Not over-reliant on self-citation
• Gives due recognition to the initial discoveries and related work that led to the work under assessment

You should be able to evaluate whether the article meets the criteria for balanced referencing without looking up every reference.

7. Plagiarism

By now you will have a deep understanding of the paper's content - and you may have some concerns about plagiarism.

Identified Concern

If you find - or already knew of - a very similar paper, this may be because the author overlooked it in their own literature search. Or it may be because it is very recent or published in a journal slightly outside their usual field.

You may feel you can advise the author how to emphasize the novel aspects of their own study, so as to better differentiate it from similar research. If so, you may ask the author to discuss their aims and results, or modify their conclusions, in light of the similar article. Of course, the research similarities may be so great that they render the work unoriginal and you have no choice but to recommend rejection.

"It's very helpful when a reviewer can point out recent similar publications on the same topic by other groups, or that the authors have already published some data elsewhere ." (Editor feedback)

Suspected Concern

If you suspect plagiarism, including self-plagiarism, but cannot recall or locate exactly what is being plagiarized, notify the editor of your suspicion and ask for guidance.

Most editors have access to software that can check for plagiarism.

Editors are not out to police every paper, but when plagiarism is discovered during peer review it can be properly addressed ahead of publication. If plagiarism is discovered only after publication, the consequences are worse for both authors and readers, because a retraction may be necessary.

For detailed guidelines see COPE's Ethical guidelines for reviewers and Wiley's Best Practice Guidelines on Publishing Ethics .

8. Search Engine Optimization (SEO)

After the detailed read-through, you will be in a position to advise whether the title, abstract and key words are optimized for search purposes. In order to be effective, good SEO terms will reflect the aims of the research.

A clear title and abstract will improve the paper's search engine rankings and will influence whether the user finds and then decides to navigate to the main article. The title should contain the relevant SEO terms early on. This has a major effect on the impact of a paper, since it helps it appear in search results. A poor abstract can then lose the reader's interest and undo the benefit of an effective title - whilst the paper's abstract may appear in search results, the potential reader may go no further.

So ask yourself, while the abstract may have seemed adequate during earlier checks, does it:

• Do justice to the manuscript in this context?
• Highlight important findings sufficiently?
• Present the most interesting data?

Editors say, " Does the Abstract highlight the important findings of the study ?"

If there is a formal report format, remember to follow it. This will often comprise a range of questions followed by comment sections. Try to answer all the questions. They are there because the editor felt that they are important. If you're following an informal report format you could structure your report in three sections: summary, major issues, minor issues.

• Give positive feedback first. Authors are more likely to read your review if you do so. But don't overdo it if you will be recommending rejection
• Briefly summarize what the paper is about and what the findings are
• Try to put the findings of the paper into the context of the existing literature and current knowledge
• Indicate the significance of the work and if it is novel or mainly confirmatory
• Indicate the work's strengths, its quality and completeness
• State any major flaws or weaknesses and note any special considerations. For example, if previously held theories are being overlooked

Major Issues

• Are there any major flaws? State what they are and what the severity of their impact is on the paper
• Has similar work already been published without the authors acknowledging this?
• Are the authors presenting findings that challenge current thinking? Is the evidence they present strong enough to prove their case? Have they cited all the relevant work that would contradict their thinking and addressed it appropriately?
• If major revisions are required, try to indicate clearly what they are
• Are there any major presentational problems? Are figures & tables, language and manuscript structure all clear enough for you to accurately assess the work?
• Are there any ethical issues? If you are unsure it may be better to disclose these in the confidential comments section

Minor Issues

• Are there places where meaning is ambiguous? How can this be corrected?
• Are the correct references cited? If not, which should be cited instead/also? Are citations excessive, limited, or biased?
• Are there any factual, numerical or unit errors? If so, what are they?
• Are all tables and figures appropriate, sufficient, and correctly labelled? If not, say which are not

Your review should ultimately help the author improve their article. So be polite, honest and clear. You should also try to be objective and constructive, not subjective and destructive.

You should also:

• Write clearly and so you can be understood by people whose first language is not English
• Avoid complex or unusual words, especially ones that would even confuse native speakers
• Number your points and refer to page and line numbers in the manuscript when making specific comments
• If you have been asked to only comment on specific parts or aspects of the manuscript, you should indicate clearly which these are
• Treat the author's work the way you would like your own to be treated

Most journals give reviewers the option to provide some confidential comments to editors. Often this is where editors will want reviewers to state their recommendation - see the next section - but otherwise this area is best reserved for communicating malpractice such as suspected plagiarism, fraud, unattributed work, unethical procedures, duplicate publication, bias or other conflicts of interest.

However, this doesn't give reviewers permission to 'backstab' the author. Authors can't see this feedback and are unable to give their side of the story unless the editor asks them to. So in the spirit of fairness, write comments to editors as though authors might read them too.

Reviewers should check the preferences of individual journals as to where they want review decisions to be stated. In particular, bear in mind that some journals will not want the recommendation included in any comments to authors, as this can cause editors difficulty later - see Section 11 for more advice about working with editors.

You will normally be asked to indicate your recommendation (e.g. accept, reject, revise and resubmit, etc.) from a fixed-choice list and then to enter your comments into a separate text box.

Recommending Acceptance

If you're recommending acceptance, give details outlining why, and if there are any areas that could be improved. Don't just give a short, cursory remark such as 'great, accept'. See Improving the Manuscript

Recommending Revision

Where improvements are needed, a recommendation for major or minor revision is typical. You may also choose to state whether you opt in or out of the post-revision review too. If recommending revision, state specific changes you feel need to be made. The author can then reply to each point in turn.

Some journals offer the option to recommend rejection with the possibility of resubmission – this is most relevant where substantial, major revision is necessary.

What can reviewers do to help? " Be clear in their comments to the author (or editor) which points are absolutely critical if the paper is given an opportunity for revisio n." (Jonathon Halbesleben, Editor of Journal of Occupational and Organizational Psychology)

Recommending Rejection

If recommending rejection or major revision, state this clearly in your review (and see the next section, 'When recommending rejection').

Where manuscripts have serious flaws you should not spend any time polishing the review you've drafted or give detailed advice on presentation.

Editors say, " If a reviewer suggests a rejection, but her/his comments are not detailed or helpful, it does not help the editor in making a decision ."

In your recommendations for the author, you should:

• Give constructive feedback describing ways that they could improve the research
• Keep the focus on the research and not the author. This is an extremely important part of your job as a reviewer
• Avoid making critical confidential comments to the editor while being polite and encouraging to the author - the latter may not understand why their manuscript has been rejected. Also, they won't get feedback on how to improve their research and it could trigger an appeal

Remember to give constructive criticism even if recommending rejection. This helps developing researchers improve their work and explains to the editor why you felt the manuscript should not be published.

" When the comments seem really positive, but the recommendation is rejection…it puts the editor in a tough position of having to reject a paper when the comments make it sound like a great paper ." (Jonathon Halbesleben, Editor of Journal of Occupational and Organizational Psychology)

Visit our Wiley Author Learning and Training Channel for expert advice on peer review.

Watch the video, Ethical considerations of Peer Review

Want to create or adapt books like this? Learn more about how Pressbooks supports open publishing practices.

13.1 Formatting a Research Paper

Learning objectives.

• Identify the major components of a research paper written using American Psychological Association (APA) style.
• Apply general APA style and formatting conventions in a research paper.

In this chapter, you will learn how to use APA style , the documentation and formatting style followed by the American Psychological Association, as well as MLA style , from the Modern Language Association. There are a few major formatting styles used in academic texts, including AMA, Chicago, and Turabian:

• AMA (American Medical Association) for medicine, health, and biological sciences
• APA (American Psychological Association) for education, psychology, and the social sciences
• Chicago—a common style used in everyday publications like magazines, newspapers, and books
• MLA (Modern Language Association) for English, literature, arts, and humanities
• Turabian—another common style designed for its universal application across all subjects and disciplines

While all the formatting and citation styles have their own use and applications, in this chapter we focus our attention on the two styles you are most likely to use in your academic studies: APA and MLA.

If you find that the rules of proper source documentation are difficult to keep straight, you are not alone. Writing a good research paper is, in and of itself, a major intellectual challenge. Having to follow detailed citation and formatting guidelines as well may seem like just one more task to add to an already-too-long list of requirements.

Following these guidelines, however, serves several important purposes. First, it signals to your readers that your paper should be taken seriously as a student’s contribution to a given academic or professional field; it is the literary equivalent of wearing a tailored suit to a job interview. Second, it shows that you respect other people’s work enough to give them proper credit for it. Finally, it helps your reader find additional materials if he or she wishes to learn more about your topic.

Furthermore, producing a letter-perfect APA-style paper need not be burdensome. Yes, it requires careful attention to detail. However, you can simplify the process if you keep these broad guidelines in mind:

• Work ahead whenever you can. Chapter 11 “Writing from Research: What Will I Learn?” includes tips for keeping track of your sources early in the research process, which will save time later on.
• Get it right the first time. Apply APA guidelines as you write, so you will not have much to correct during the editing stage. Again, putting in a little extra time early on can save time later.
• Use the resources available to you. In addition to the guidelines provided in this chapter, you may wish to consult the APA website at http://www.apa.org or the Purdue University Online Writing lab at http://owl.english.purdue.edu , which regularly updates its online style guidelines.

General Formatting Guidelines

This chapter provides detailed guidelines for using the citation and formatting conventions developed by the American Psychological Association, or APA. Writers in disciplines as diverse as astrophysics, biology, psychology, and education follow APA style. The major components of a paper written in APA style are listed in the following box.

These are the major components of an APA-style paper:

Body, which includes the following:

• Headings and, if necessary, subheadings to organize the content
• In-text citations of research sources
• References page

All these components must be saved in one document, not as separate documents.

The title page of your paper includes the following information:

• Title of the paper
• Author’s name
• Name of the institution with which the author is affiliated
• Header at the top of the page with the paper title (in capital letters) and the page number (If the title is lengthy, you may use a shortened form of it in the header.)

List the first three elements in the order given in the previous list, centered about one third of the way down from the top of the page. Use the headers and footers tool of your word-processing program to add the header, with the title text at the left and the page number in the upper-right corner. Your title page should look like the following example.

The next page of your paper provides an abstract , or brief summary of your findings. An abstract does not need to be provided in every paper, but an abstract should be used in papers that include a hypothesis. A good abstract is concise—about one hundred fifty to two hundred fifty words—and is written in an objective, impersonal style. Your writing voice will not be as apparent here as in the body of your paper. When writing the abstract, take a just-the-facts approach, and summarize your research question and your findings in a few sentences.

In Chapter 12 “Writing a Research Paper” , you read a paper written by a student named Jorge, who researched the effectiveness of low-carbohydrate diets. Read Jorge’s abstract. Note how it sums up the major ideas in his paper without going into excessive detail.

Write an abstract summarizing your paper. Briefly introduce the topic, state your findings, and sum up what conclusions you can draw from your research. Use the word count feature of your word-processing program to make sure your abstract does not exceed one hundred fifty words.

Depending on your field of study, you may sometimes write research papers that present extensive primary research, such as your own experiment or survey. In your abstract, summarize your research question and your findings, and briefly indicate how your study relates to prior research in the field.

Margins, Pagination, and Headings

APA style requirements also address specific formatting concerns, such as margins, pagination, and heading styles, within the body of the paper. Review the following APA guidelines.

Use these general guidelines to format the paper:

• Set the top, bottom, and side margins of your paper at 1 inch.
• Use double-spaced text throughout your paper.
• Use a standard font, such as Times New Roman or Arial, in a legible size (10- to 12-point).
• Use continuous pagination throughout the paper, including the title page and the references section. Page numbers appear flush right within your header.
• Section headings and subsection headings within the body of your paper use different types of formatting depending on the level of information you are presenting. Additional details from Jorge’s paper are provided.

Begin formatting the final draft of your paper according to APA guidelines. You may work with an existing document or set up a new document if you choose. Include the following:

• Your title page
• The abstract you created in Note 13.8 “Exercise 1”
• Correct headers and page numbers for your title page and abstract

APA style uses section headings to organize information, making it easy for the reader to follow the writer’s train of thought and to know immediately what major topics are covered. Depending on the length and complexity of the paper, its major sections may also be divided into subsections, sub-subsections, and so on. These smaller sections, in turn, use different heading styles to indicate different levels of information. In essence, you are using headings to create a hierarchy of information.

The following heading styles used in APA formatting are listed in order of greatest to least importance:

• Section headings use centered, boldface type. Headings use title case, with important words in the heading capitalized.
• Subsection headings use left-aligned, boldface type. Headings use title case.
• The third level uses left-aligned, indented, boldface type. Headings use a capital letter only for the first word, and they end in a period.
• The fourth level follows the same style used for the previous level, but the headings are boldfaced and italicized.
• The fifth level follows the same style used for the previous level, but the headings are italicized and not boldfaced.

Visually, the hierarchy of information is organized as indicated in Table 13.1 “Section Headings” .

Table 13.1 Section Headings

A college research paper may not use all the heading levels shown in Table 13.1 “Section Headings” , but you are likely to encounter them in academic journal articles that use APA style. For a brief paper, you may find that level 1 headings suffice. Longer or more complex papers may need level 2 headings or other lower-level headings to organize information clearly. Use your outline to craft your major section headings and determine whether any subtopics are substantial enough to require additional levels of headings.

Working with the document you developed in Note 13.11 “Exercise 2” , begin setting up the heading structure of the final draft of your research paper according to APA guidelines. Include your title and at least two to three major section headings, and follow the formatting guidelines provided above. If your major sections should be broken into subsections, add those headings as well. Use your outline to help you.

Because Jorge used only level 1 headings, his Exercise 3 would look like the following:

Citation Guidelines

In-text citations.

Throughout the body of your paper, include a citation whenever you quote or paraphrase material from your research sources. As you learned in Chapter 11 “Writing from Research: What Will I Learn?” , the purpose of citations is twofold: to give credit to others for their ideas and to allow your reader to follow up and learn more about the topic if desired. Your in-text citations provide basic information about your source; each source you cite will have a longer entry in the references section that provides more detailed information.

In-text citations must provide the name of the author or authors and the year the source was published. (When a given source does not list an individual author, you may provide the source title or the name of the organization that published the material instead.) When directly quoting a source, it is also required that you include the page number where the quote appears in your citation.

This information may be included within the sentence or in a parenthetical reference at the end of the sentence, as in these examples.

Epstein (2010) points out that “junk food cannot be considered addictive in the same way that we think of psychoactive drugs as addictive” (p. 137).

Here, the writer names the source author when introducing the quote and provides the publication date in parentheses after the author’s name. The page number appears in parentheses after the closing quotation marks and before the period that ends the sentence.

Addiction researchers caution that “junk food cannot be considered addictive in the same way that we think of psychoactive drugs as addictive” (Epstein, 2010, p. 137).

Here, the writer provides a parenthetical citation at the end of the sentence that includes the author’s name, the year of publication, and the page number separated by commas. Again, the parenthetical citation is placed after the closing quotation marks and before the period at the end of the sentence.

As noted in the book Junk Food, Junk Science (Epstein, 2010, p. 137), “junk food cannot be considered addictive in the same way that we think of psychoactive drugs as addictive.”

Here, the writer chose to mention the source title in the sentence (an optional piece of information to include) and followed the title with a parenthetical citation. Note that the parenthetical citation is placed before the comma that signals the end of the introductory phrase.

David Epstein’s book Junk Food, Junk Science (2010) pointed out that “junk food cannot be considered addictive in the same way that we think of psychoactive drugs as addictive” (p. 137).

Another variation is to introduce the author and the source title in your sentence and include the publication date and page number in parentheses within the sentence or at the end of the sentence. As long as you have included the essential information, you can choose the option that works best for that particular sentence and source.

Citing a book with a single author is usually a straightforward task. Of course, your research may require that you cite many other types of sources, such as books or articles with more than one author or sources with no individual author listed. You may also need to cite sources available in both print and online and nonprint sources, such as websites and personal interviews. Chapter 13 “APA and MLA Documentation and Formatting” , Section 13.2 “Citing and Referencing Techniques” and Section 13.3 “Creating a References Section” provide extensive guidelines for citing a variety of source types.

Writing at Work

APA is just one of several different styles with its own guidelines for documentation, formatting, and language usage. Depending on your field of interest, you may be exposed to additional styles, such as the following:

• MLA style. Determined by the Modern Languages Association and used for papers in literature, languages, and other disciplines in the humanities.
• Chicago style. Outlined in the Chicago Manual of Style and sometimes used for papers in the humanities and the sciences; many professional organizations use this style for publications as well.
• Associated Press (AP) style. Used by professional journalists.

References List

The brief citations included in the body of your paper correspond to the more detailed citations provided at the end of the paper in the references section. In-text citations provide basic information—the author’s name, the publication date, and the page number if necessary—while the references section provides more extensive bibliographical information. Again, this information allows your reader to follow up on the sources you cited and do additional reading about the topic if desired.

The specific format of entries in the list of references varies slightly for different source types, but the entries generally include the following information:

• The name(s) of the author(s) or institution that wrote the source
• The year of publication and, where applicable, the exact date of publication
• The full title of the source
• For books, the city of publication
• For articles or essays, the name of the periodical or book in which the article or essay appears
• For magazine and journal articles, the volume number, issue number, and pages where the article appears
• For sources on the web, the URL where the source is located

The references page is double spaced and lists entries in alphabetical order by the author’s last name. If an entry continues for more than one line, the second line and each subsequent line are indented five spaces. Review the following example. ( Chapter 13 “APA and MLA Documentation and Formatting” , Section 13.3 “Creating a References Section” provides extensive guidelines for formatting reference entries for different types of sources.)

In APA style, book and article titles are formatted in sentence case, not title case. Sentence case means that only the first word is capitalized, along with any proper nouns.

Key Takeaways

• Following proper citation and formatting guidelines helps writers ensure that their work will be taken seriously, give proper credit to other authors for their work, and provide valuable information to readers.
• Working ahead and taking care to cite sources correctly the first time are ways writers can save time during the editing stage of writing a research paper.
• APA papers usually include an abstract that concisely summarizes the paper.
• APA papers use a specific headings structure to provide a clear hierarchy of information.
• In APA papers, in-text citations usually include the name(s) of the author(s) and the year of publication.
• In-text citations correspond to entries in the references section, which provide detailed bibliographical information about a source.

Writing for Success Copyright © 2015 by University of Minnesota is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License , except where otherwise noted.

Reference management. Clean and simple.

Literature review

How to write a literature review in 6 steps

How do you write a good literature review? This step-by-step guide on how to write an excellent literature review covers all aspects of planning and writing literature reviews for academic papers and theses.

How to write a systematic literature review [9 steps]

How do you write a systematic literature review? What types of systematic literature reviews exist and where do you use them? Learn everything you need to know about a systematic literature review in this guide

What is a literature review? [with examples]

Not sure what a literature review is? This guide covers the definition, purpose, and format of a literature review.

How to write the literature review of your research paper

Study Background & Introduction

Dr. Rishibha Sachdev

Many researchers struggle when it comes to writing literature review for their research paper. A literature review is a comprehensive overview of all the knowledge available on a specific topic till date. When you decide on a research topic, usually the first step you take in the direction of conducting research is learn more about the previous research published on the topic, and this eventually translates into literature review when you write your research paper. Literature review is one of the pillars on which your research idea stands since it provides context, relevance, and background to the research problem you are exploring.  

Types of literature review

Theoretical literature review essentially involves two steps: 

• Surveying and critically reading the existing literature: this step is commonly referred to as experimental literature review.
• Summarizing and actually penning down the gist of your review in an organized manner: this is known as theoretical review.

Literature review could be a part of a dissertation or research article and a stand-alone literature review. Let us look at this in more detail.

Literature reviews for dissertation/research article

Every research report/ thesis/research article begins with an introduction to the topic of research. This forms the literature review for the article. The main purpose of the review is to introduce the readers to the need for conducting the said research. A literature review should begin with a thorough literature search using the main keywords in relevant online databases such as Google Scholar , PubMed , etc. Once all the relevant literature has been gathered, it should be organized as follows:

• Background literature about the broad research topic to introduce the readers to the field of study.
• Recent progress on the study topic which can be organized thematically or chronologically. Ideally, separate themes should be discussed in a chronological manner to describe how research in the field has evolved over time and to highlight the progress in the field.
• The review should include a comparison and contrast of different studies. Discussing the controversial aspects helps to identify the main gaps that need to be worked upon. This is essential for defining the problem statement of the study and highlighting the significance of the research under question.
• Once a problem statement has been defined, the strengths and pitfalls of other studies that have tackled the problem statement should be discussed. This is important for outlining the need and novelty of the research.

A literature review should not be a mere recounting of all the available information. It should be a critical and analytical summary of the selected literature that guides the readers through the central theme of the research.

Does your publication goal seem near yet too far? Explore the #POWERofMORE – the boost you need to achieve all your goals Click here to know more!   

Stand-alone literature reviews

Literature reviews can also be written as stand-alone articles. These are not different from the literature review sections described above; however, they are not followed by experimental data.

They basically fall into 2 broad categories: narrative reviews and systematic reviews.

1. Narrative reviews

These are theoretical discussions of relevant information on a particular topic and its critical analysis. These are mostly qualitative in nature similar to the review sections of larger articles.

Narrative reviews are usually organized as follows:

Introduction that establishes the context of the field of research and the topic of the review

Body is normally used for describing the different themes under the main topic by dividing them into different subheadings. This section compares and contrasts published studies and identifies gaps that have not been addressed or have been unsuccessfully addressed.

Conclusions. This section differs slightly between reviews which are part of research articles and narrative reviews. The section describes the main conclusions from analysis of all the current studies and puts forth further avenues for research. This section requires critical interpretation by the author such that the review adds value to existing literature. It should bring out ideas/hypotheses that can explain any discrepancies and provide solutions to existing problems.

2. Systematic reviews

On the other hand, systematic reviews follow a well-planned methodology to qualitatively or quantitatively analyze a defined number of studies. They usually focus on a single question and have clear study objectives that are worked upon in a systematic manner. These studies are based on a well-defined strategy unlike narrative reviews. Systematic reviews and narrative reviews are organized slightly differently. The details are described below:

Introduction: Systematic reviews begin with specific research questions that are defined in terms of the samples and research outcomes to be studied.

Methods (only for systematic reviews):  These studies have a comprehensive methodology that starts by narrowing down the literature for the review. Usually, specific inclusion/exclusion criteria are set based on the research questions and databases are searched based on these criteria. Once the sample studies have been shortlisted, they are analyzed in detail.

Results: The results section for these studies involves comprehensive data analysis to determine the significance of the study outcomes. Systematic reviews can be accompanied with Meta-analysis which involves statistical analysis of the included studies to increase the power of the results.

Discussion: This section usually interprets the study data based on their weighted significance and the power of the results. The study therefore provides strengthened results that are validated by the scientific rigor of the analytical method.

Before starting to write a review, it is important to determine what kind of review you want to write and follow the appropriate style and guidelines. An effective literature review is important for the complete life cycle of a research from defining the right research goals to correctly interpreting and presenting the research results.

If you wish to learn in more depth how to conduct literature search, check out this course designed exclusively for researchers:  How to conduct an effective literature search and review .

Bonus takeaway exclusively for community members

Writing a literature review requires you to read through and collate several research articles and literature sources. This can get very confusing considering the large amount of publications that need to be organized. There is no set way to do this as it will depend on your preference for reading printed articles or online resources. If you are old school and read printed articles better, then you should create a folder with all articles organized in this way:

1. Alphabetically with the last name of the first author, or

2. Chronologically with the date of publication, or

3. Thematically with different themes organized chronologically

For the more tech-savy users, organization of literature either by year of publication or themes would be more ideal. Citing and creating a reference list in your manuscript can be done either manually or by using reference management tools like Endnote from Clarivate analytics. Endnote is an excellent way to store your research library and import it into the manuscript in the format required by the journal.

The tips and guidelines in this post should help you write your literature review with ease.

Related reading: 

• A young researcher's guide to writing a literature review
• 5 Tips to write a great literature review

References:

• Tips for effective literature searching and keeping up with new publications
• Writing a Literature Review
• Systematic literature review X narrative review
• Systematic Reviews: What is a systematic review?

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Writing a law school research paper or law review note

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Basics of Format & Content

Research papers are not as strictly structured as legal memos, briefs, and other documents that you've learned about in legal writing and drafting courses. For example, there is no prescribed content/format similar to to the Questions Presented, Brief Answers, etc. that you learned for a legal memo.

A general approach to thinking about the content of a research paper is:

• Introduction in which you give some background and a clear statement of your thesis
• Status quo -- what is the existing law and why is it a problem
• Proposals for change

See this blog post by Jonathan Burns, and IU McKinney alum, for more on basic content.

If you're writing for a law review or seminar, you should get formatting instructions regarding things like margins, font size, line spacing. If you don't, or if you're doing an independent study, here are some basic guidelines to follow:

• Times New Roman or similar, 12 pt font.
• Double spaced lines.
• One inch margins all around.
• Footnotes in academic Bluebook style (use the rules on the main white pages instead of the light blue pages at the front of the Bluebook).
• Footnotes in same font as text, 10 pt font.
• Use Roman numerals and/or letters on headings and subheadings or style the fonts so that the difference between headings and subheadings is clear.   
• Page numbers in the footer, preferably centered, especially on first page. You could do bottom center on first page and then upper right in the header thereafter. Use the header and footer functions for this. If you don't know how to use headers and footers in Word, here is help:  https://edu.gcfglobal.org/en/word2016/headers-and-footers/1/ . 

Headings and subheadings

Research papers should have headings and subheadings. These help your reader follow your logic--and a logical structure is very important. Headings and subheadings can also help you keep your thoughts organized. Just don't overuse them--you don't want every paragaph to have a subheading. 

Road map paragraph

Often, research papers will also include a paragraph at the end of the introduction that narrates the road map the paper will follow.   Here is an example of this kind of paragraph:

"The section that follows [this introduction] sets the stage by recounting two scenarios from the Indiana University Robert H. McKinney School of Law, with discussion of the knowledge and implementation of accessibility features in online instructional materials. The next section provides an overview of various impairments and their effects on a user's experience of the online environment. Next is a review of the laws relevant to accessibility with attention to their potential application to online instruction, along with standards used to guide accessibility compliance. The article then explores the concept of universal design and its guiding principles, followed by a discussion of how to use the universal design principles to organize and better understand accessibility standards and practices. The final section briefly summarizes the discussion and encourages law librarians and professors to become knowledgeable and skilled in universal design for online materials to benefit all their students."

Table of Contents

A table of contents can also be helpful, though it's not necessary. If you add a table of contents to your papers, put it right at the beginning, before the introduction. Here's part of the table of contents for the same paper the paragraph above was taken from--it really just lays out the heading and subheadings with page numbers: 

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Literature Review: Conducting & Writing

• Sample Literature Reviews
• Steps for Conducting a Lit Review
• Finding "The Literature"
• Organizing/Writing
• APA Style This link opens in a new window
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Sample Lit Reviews from Communication Arts

Have an exemplary literature review.

• Literature Review Sample 1
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• Literature Review Sample 3

Have you written a stellar literature review you care to share for teaching purposes?

Are you an instructor who has received an exemplary literature review and have permission from the student to post?

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A small brain sample was sliced into 5,000 pieces, and machine learning helped stitch it back together.

• Cassandra Willyard archive page

A team led by scientists from Harvard and Google has created a 3D, nanoscale-resolution map of a single cubic millimeter of the human brain. Although the map covers just a fraction of the organ—a whole brain is a million times larger—that piece contains roughly 57,000 cells, about 230 millimeters of blood vessels, and nearly 150 million synapses. It is currently the highest-resolution picture of the human brain ever created.

To make a map this finely detailed, the team had to cut the tissue sample into 5,000 slices and scan them with a high-speed electron microscope. Then they used a machine-learning model to help electronically stitch the slices back together and label the features. The raw data set alone took up 1.4 petabytes. “It’s probably the most computer-intensive work in all of neuroscience,” says Michael Hawrylycz, a computational neuroscientist at the Allen Institute for Brain Science, who was not involved in the research. “There is a Herculean amount of work involved.”

Many other brain atlases exist, but most provide much lower-resolution data. At the nanoscale, researchers can trace the brain’s wiring one neuron at a time to the synapses, the places where they connect. “To really understand how the human brain works, how it processes information, how it stores memories, we will ultimately need a map that’s at that resolution,” says Viren Jain, a senior research scientist at Google and coauthor on the paper, published in Science on May 9 . The data set itself and a preprint version of this paper were released in 2021 .

Brain atlases come in many forms. Some reveal how the cells are organized. Others cover gene expression. This one focuses on connections between cells, a field called “connectomics.” The outermost layer of the brain contains roughly 16 billion neurons that link up with each other to form trillions of connections. A single neuron might receive information from hundreds or even thousands of other neurons and send information to a similar number. That makes tracing these connections an exceedingly complex task, even in just a small piece of the brain..  

To create this map, the team faced a number of hurdles. The first problem was finding a sample of brain tissue. The brain deteriorates quickly after death, so cadaver tissue doesn’t work. Instead, the team used a piece of tissue removed from a woman with epilepsy during brain surgery that was meant to help control her seizures.

Once the researchers had the sample, they had to carefully preserve it in resin so that it could be cut into slices, each about a thousandth the thickness of a human hair. Then they imaged the sections using a high-speed electron microscope designed specifically for this project. 

Next came the computational challenge. “You have all of these wires traversing everywhere in three dimensions, making all kinds of different connections,” Jain says. The team at Google used a machine-learning model to stitch the slices back together, align each one with the next, color-code the wiring, and find the connections. This is harder than it might seem. “If you make a single mistake, then all of the connections attached to that wire are now incorrect,” Jain says. 

“The ability to get this deep a reconstruction of any human brain sample is an important advance,” says Seth Ament, a neuroscientist at the University of Maryland. The map is “the closest to the  ground truth that we can get right now.” But he also cautions that it’s a single brain specimen taken from a single individual. 

The map, which is freely available at a web platform called Neuroglancer , is meant to be a resource other researchers can use to make their own discoveries. “Now anybody who’s interested in studying the human cortex in this level of detail can go into the data themselves. They can proofread certain structures to make sure everything is correct, and then publish their own findings,” Jain says. (The preprint has already been cited at least 136 times .) 

The team has already identified some surprises. For example, some of the long tendrils that carry signals from one neuron to the next formed “whorls,” spots where they twirled around themselves. Axons typically form a single synapse to transmit information to the next cell. The team identified single axons that formed repeated connections—in some cases, 50 separate synapses. Why that might be isn’t yet clear, but the strong bonds could help facilitate very quick or strong reactions to certain stimuli, Jain says. “It’s a very simple finding about the organization of the human cortex,” he says. But “we didn’t know this before because we didn’t have maps at this resolution.”

The data set was full of surprises, says Jeff Lichtman, a neuroscientist at Harvard University who helped lead the research. “There were just so many things in it that were incompatible with what you would read in a textbook.” The researchers may not have explanations for what they’re seeing, but they have plenty of new questions: “That’s the way science moves forward.” 

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• Matters Arising
• Open access
• Published: 13 May 2024

Extrapolation errors in Liu et al.’s CAM integrative review of health care professionals in New Zealand

• Jillian Marie McDowell   ORCID: orcid.org/0000-0003-4351-9817 1 ,
• Susan Heather Kohut 2 &
• Debra Betts 3  

BMC Complementary Medicine and Therapies volume  24 , Article number:  187 ( 2024 ) Cite this article

16 Accesses

Metrics details

Matters Arising to this article was published on 13 May 2024

The Original Article was published on 13 February 2021

This letter is to highlight errors made by Liu et al. in their 2020 paper in BMC Complementary Medicine and Therapies, “Complementary and alternative medicine—practice, attitudes, and knowledge among healthcare professionals in New Zealand: an integrative review”. Substantial errors in their citation of the recent research and methodology by McDowell, Kohut & Betts (2019) pertaining to the practice of acupuncture in New Zealand by physiotherapists are presented. The actual results of McDowell et al.’s work and the true state of acupuncture use by their sample group is reported.

Peer Review reports

This letter is to highlight errors made by Liu et al. in their 2020 paper in BMC Complementary Medicine and Therapies, “Complementary and alternative medicine—practice, attitudes, and knowledge among healthcare professionals in New Zealand: an integrative review” [ 1 ], when citing the paper “Safe acupuncture and dry needling during pregnancy: A survey of New Zealand physiotherapists’ practice”, published in 2019 in Integrative Medicine Research [ 2 ]. Extrapolation errors are evident in their abstract, results and discussion’s statistics. Furthermore, the methodology has been mis-cited, as has interpretation of postgraduate physiotherapy acupuncture training in New Zealand (NZ).

Extrapolation errors – statistical

In Liu et al.’s abstract on complementary and alternative medicine (CAM) they state:

“When treating pregnant women, 48.4% of physiotherapists practise acupuncture , and 37.3% of midwives recommend CAM” page 1 [ 1 ].

These statistics are repeated in their results section for prevalence of practice, use and referral for CAM:

“Findings indicated that around 25% of GPs practise CAM, and 82.3% refer patients to CAM practitioners. When treating pregnant women, 48.4% of physiotherapists practise acupuncture, and 37.3% of midwives recommend CAM” page 4 [ 1 ],

and again, in their discussion:

“Findings indicated that CAM use is common among New Zealand healthcare professionals: around 25% of GPs practise CAM, and 82.3% refer patients to CAM practitioners; when treating pregnant women, 48.4% of physiotherapists practise acupuncture, and 37.3% of midwives recommend CAM” page 7 [ 1 ].

More accurately McDowell et al. [ 2 ] reported that 60 physiotherapists (48.4% of the 124 total respondents) practise acupuncture during pregnancy. This represented 0.8% of the 7337 registered physiotherapists in NZ. Liu et al.’s citation would infer that 48.4% of all registered physiotherapists in NZ (3551/7337) practice acupuncture for pregnant women; a 60-fold overestimation. McDowell et al. very clearly reported the limitations of their study;

“The results of this purposive study may not be indicative of the opinion of all NZ physiotherapy acupuncturists and dry needlers” page 37 [ 2 ] ,

and Liu et al.’s interpretative flaws may lead to future publication errors if it is cited further.

Extrapolation error—Post graduate training

The following statement in Liu et al.’s paper is inaccurate and misleading.

“Findings indicated that approximately one quarter of GPs have received formal training in CAM, while 44.4% of physiotherapist received (postgraduate) training in acupuncture” page 6 [ 1 ].

More correctly 53% of physiotherapists ( n  = 32) of those who answered in the affirmative to McDowell et al.’s survey, (i.e., who would provide acupuncture during pregnancy), had undergone post-graduate training with a resulting university-based qualification. It is important to note that physiotherapists choose to study and practice acupuncture in NZ as a postgraduate competency. Yet again Liu et al. have committed a statistical error of extrapolating a very small survey finding to the entire NZ physiotherapy population.

Methodology citation error

In their paper Liu et al. also state:

“Instruments used in the eight surveys varied, without psychometric properties reported; four studies used instruments that were developed and adapted from previous studies” . page 4 [ 1 ].

McDowell et al.’s paper clearly describes the development of the electronic survey questionnaire, expert peer review, and piloting prior to the main survey. It was not adapted from a previous study as cited by Liu et al. above.

The current state of acupuncture practice in NZ by physiotherapists

The practice of acupuncture is not currently regulated for physiotherapists in NZ, being considered “a modality within the practice of physiotherapy” [ 3 ]. Registered physiotherapists may practice within a defined field of practice as autonomous practitioners but must “complete or be currently undertaking, relevant, sufficient, and appropriate education and training and continuing professional development to maintain such knowledge and competence” [ 4 ]. NZ registered physiotherapists who have gained post graduate qualifications in acupuncture or have trained in dry needing are termed “physiotherapy acupuncturists” to identify as a separate profession to acupuncturists.

At the time of the survey 7337 physiotherapists were registered to practice in NZ [ 5 ]. Sixty nine percent of those were members of their national society, Physiotherapy New Zealand (PNZ) [ 6 ], and only 310 were members of PNZ’s special interest group the Physiotherapy Acupuncture Association of New Zealand (PAANZ). Further demographic information on the total number of NZ physiotherapists who have undertaken relevant education or who are currently practicing needling was not available.

Acupuncture has been taught and practiced by physiotherapists in NZ since 1992 [ 7 , 8 , 9 ]. However, the total number of physiotherapists utilising this complementary and alternative medicine in NZ is unknown. This has been a limiting factor for several research surveys to date [ 10 , 11 ]. The paper “Safe acupuncture and dry needling during pregnancy: New Zealand physiotherapists’ opinion and practice”, was published in 2019 in Integrative Medicine Research [ 2 ]. It is important to emphasise that the paper’s results did not have access to the entire population of potential respondents. The Privacy Act of New Zealand [ 12 ] prohibits the direct use of Physiotherapy Board of New Zealand (PBNZ) membership lists to target the entire survey population. McDowell et al.’s survey recruitment was via invitation only by PNZ e-mail, with additional links available through PAANZ and PNZ webpages, closed acupuncture group Facebook pages and physiotherapy newsletters within NZ.

Whilst McDowell et al.’s primary aim was to gather basic demographics and examine the opinions, practice and level of understanding held by NZ physiotherapy acupuncturists providing acupuncture and dry needling for pregnant women, their results were never intended to be reflective of the entire population of physiotherapists in New Zealand.

Regrettably, this fact seems to have been lost by Liu et al. when extrapolating McDowell et al.’s data as verbatim statistics for the entire NZ physiotherapy population.

Survey response rates have been on the decline for the past decade in the field of health related research [ 13 , 14 ], with response rates consistently lower than those of surveys of the general population [ 15 ]. Field et al. [ 16 ] reported response rates of between 13 and 39% are common in healthcare research. Cunningham et al. [ 13 ] found an overall response rate of 35% amongst physicians in Canada on a sensitive topic (medical billing practices) which was comparable to 39.6% response rate reported in the meta-analysis by Cook [ 17 ]. The McDowell et al.’s survey noted the existence of a low response rate (particularly from physiotherapy acupuncturists with only dry needling training), and a high number of missing responses within individual responses. This sample may not represent any definable population larger than NZ physiotherapy acupuncturists, a concept that appears to have been neglected by Liu et al.’s integrative review [ 1 ].

Further research

Research-based practice is central to improving the quality of health care by obtaining information about the knowledge, attitudes, practice patterns, the needs of practitioners [ 18 ] and to evaluate the impact of clinical research on practice [ 13 ]. Soliciting practitioner input is also essential when existing healthcare policies are being updated or to inform new policies [ 19 ].

Liu et al. have failed to recognize the limitations of McDowell et al.’s research sample, thus committing a statistical error of extrapolating a small survey finding to the entire NZ physiotherapy population. This raises concern that others may read their paper and cite it further (especially with the error prominent in the abstract), compounding errors in perceived practice if they are compared to the inflated NZ data. To date four papers have cited Liu et al.’s paper [ 20 , 21 , 22 , 23 ], fortunately without specifically referring to the erroneous sections. We ask that Lui et al.’s statements be corrected via publication of this correspondence, that is indexed and bidirectionally linked to the original article to prevent further and future errors.

Availability of data and materials

Not applicable.

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Acknowledgements

No funding was received for the original survey “Safe acupuncture and dry needling during pregnancy: New Zealand physiotherapists’ opinion and practice”. A prize to encourage participant completion of the survey was donated by AcuFuture, NZ.

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Jillian Marie McDowell

School of Clinical Sciences, Faculty of Health and Environmental Sciences, Auckland University of Technology, Auckland, New Zealand

Susan Heather Kohut

New Zealand School of Acupuncture and Traditional Chinese Medicine, Wellington, New Zealand

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JM, SK and DB were the authors of the original paper. JM drafted the letter. All authors read and approved the final version.

Corresponding author

Correspondence to Jillian Marie McDowell .

Ethics declarations

Ethics approval and consent to participate.

The survey referred to in this correspondence was undertaken with an electronic questionnaire. Ethics approval for this study was granted by the Auckland University of Technology Ethics Committee, application number 17/100. Participants were provided with an explanation of the study, consent details and researcher contact details.

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Not applicable (No identifying data).

Competing interests

JM and SK are executive members of, and tutors for the Physiotherapy Acupuncture Association of New Zealand (PAANZ). They are responsible for updating the PAANZ Guidelines for Safe Acupuncture practice biannually. SK is on the executive of International Acupuncture Association of Physical Therapists. DB is employed by the New Zealand School of Acupuncture and Traditional Chinese Medicine as a supervisor for a maternity acupuncture clinic at Hutt Valley Hospital, New Zealand.

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McDowell, J.M., Kohut, S.H. & Betts, D. Extrapolation errors in Liu et al.’s CAM integrative review of health care professionals in New Zealand. BMC Complement Med Ther 24 , 187 (2024). https://doi.org/10.1186/s12906-023-04259-3

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Received : 21 September 2021

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Published : 13 May 2024

DOI : https://doi.org/10.1186/s12906-023-04259-3

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